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Vitamin E API Vacuum Single Cone Dryer

所属分类:工程案例 > 真空干燥设备工程案例 > 维生素E原料药真空单锥干燥机

案例简介:Case Introduction:With the increasing awareness of environmental protection and the tightening of environmental policies, vitamin E API manufacturers are facing greater environmental pressure. Enterprises need to increase investment in environmental protection, the use of more environmentally friendly production processes and equipment, reduce wastewater, waste gas, waste residue emissions to meet environmental requirements. Jiangsu Bohong continuously invested in research and development resources to improve the drying process of vitamin E, improve production efficiency, reduce costs and reduce environmental pollution. R & D of vitamin E API vacuum single cone dryer to solve the existing equipment in the production of low production efficiency, product quality is not stable and so on, with high production efficiency, product quality is stable, automation degree of high advantages, and gradually become the development trend of vitamin E API production.

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Vitamin E is a fat-soluble vitamin. As a medicine, vitamin E is used in the treatment of habitual abortion, preeclampsia, infertility and other reproductive diseases, and is also used in the adjuvant treatment of cardiovascular diseases, certain neurological diseases and various symptoms caused by vitamin E deficiency. As a food additive, vitamin E is mainly used for antioxidant preservation of fats and oils, meat products, dairy products and other foods, which can extend the shelf life of food, prevent the oxidation and rancidity of fats and oils in food, and maintain the flavor and nutrition of food. Domestic vitamin E API manufacturers have been developing and growing, and their share in the global market is gradually increasing. Domestic enterprises excel in technological innovation, product quality and cost control, with strong market competitiveness. With the continuous development of domestic enterprises, it is expected to further enhance the right to speak in the global vitamin E API market and promote the development of the industry.


With the enhancement of environmental protection awareness and environmental protection policies tend to tighten, vitamin E API manufacturers are facing greater environmental pressure. Enterprises need to increase investment in environmental protection, the use of more environmentally friendly production processes and equipment, reduce wastewater, waste gas, waste emissions, to meet environmental requirements, Jiangsu Bo Hong constantly invest in research and development resources to improve the drying process of vitamin E. The drying process can improve production efficiency, reduce costs and reduce environmental pollution, research and development of vitamin E API straight air single fault drying. Improve production efficiency, reduce costs and reduce environmental pollution, the research and development of vitamin E API straight air single error dryer to solve the existing equipment in the production of low production efficiency, product quality is not stable and other issues, with high production efficiency, product quality and stability, automation and other advantages, and gradually become the development trend of vitamin E API production. The new equipment with the help of advanced information technology to achieve intelligent control and management of vitamin E production process. Through real-time monitoring, analysis and prediction of production data, it can optimize the parameters of production process, improve the stability and controllability of production, and reduce the production cost and quality risk.


Vitamin E API Vacuum Single Cone Dryer Process Flow

(1) Feed preparation: first check the equipment status of the vacuum single-cone dryer to ensure that the equipment is intact, the normal operation of the components, no leakage and other issues. Then the vitamin raw materials to be dried ready, the general requirements of the material particle size and moisture content and other indicators in line with the scope of application of the dryer.

(2) feeding: through the feeding device will be vitamin E API materials slowly added to the vacuum single-cone dryer inside, in the feeding process, pay attention to the control of feeding speed and feeding volume, to avoid feeding too fast resulting in uneven accumulation of materials, affecting the drying effect, usually loaded with the amount of control in the container of the effective volume of 30% -80% or so.

(3) vacuum: after closing the feed port, start the vacuum pump, the dryer internal air extraction, so that the drying chamber gradually form a certain degree of vacuum, the general vacuum required to reach 0.01-0.1MPa or so. In a vacuum environment, the boiling point of water or organic solvents in vitamin E API will be significantly reduced, thereby accelerating the drying speed.

(4) Heating and drying: open the heating jacket of the heating medium valve, so that hot water, steam or thermal oil and other heating medium into the jacket, the heat through the container wall transfer to the material. At the same time, start the stirring device, stirring paddle to the appropriate speed spinning generally in 5-20 rpm, so that the material in the drying process is fully turned, increasing the contact area between the material and the heating surface, to ensure that the material is heated uniformly, to avoid localized overheating and agglomeration phenomenon, improve the drying efficiency and quality. Turning.

(5) Drying process monitoring: in the drying process, through the temperature sensor, vacuum sensor and other equipment real-time monitoring of the temperature and vacuum in the dryer, and adjusted according to the preset drying parameters, when the moisture content of the material or solvent residue to meet the required standards, the drying process ends. In this process, the operator needs to pay close attention to the changes in the parameters to ensure the stability and reliability of the drying process.

(6) break the air and discharge: close the heating medium valve and vacuum pump, to be returned to normal pressure inside the dryer, open the discharge port, the dried vitamin E raw materials discharged. Discharge should pay attention to avoid contamination or loss of materials, you can use the appropriate discharge device, such as screw conveyor, etc., the material will be transported to the designated packaging or storage location.

(7) Equipment cleaning and maintenance: After the discharge is completed, the vacuum single cone dryer is cleaned up to remove the residual materials and impurities inside, and then the equipment is checked and maintained to ensure the performance and stability of the equipment when it is used next time.


Vitamin E API Vacuum Single Cone Dryer Performance Features

(1)Large production capacity: large loading capacity, generally up to about 80% of the effective volume of the container, suitable for large-scale production of vitamin E API, improve production efficiency.

(2)High drying efficiency

Large effective heat transfer area: its effective heat transfer area is about 1.7 times of the inner area of the container, which can make the material fully absorb heat and speed up the drying speed.

The material movement is sufficient: the material is lifted up in the spiral in the vessel, and then descends along the main axis in a vortex, and is heated evenly and effectively in this dispersed movement, which improves the uniformity and efficiency of drying.

Optimization of vacuum system: The combination of high vacuum at the head of the machine and high-speed pulse airflow at the bottom of the machine with the same temperature in the same direction can efficiently take away the solvent in the material. At the same time, the design of double-channel vacuum pipe opening prevents vacuum blockage, reduces resistance, improves pumping rate and further accelerates the drying process.

(3)Product quality guarantee

Full-sealed nitrogen-filled production: the drying process is fully sealed and can be filled with nitrogen protection, avoiding material contact with the air, preventing oxidation and deterioration, guaranteeing product quality, but also reducing the cross and pollution, improving the cleanliness and safety level.

Prevent material bonding: the gap between the mixer and the container wall is small, and high finish, can effectively prevent the material bonded to the surface of the wall, to ensure that the material can be fully dry, but also to facilitate the cleaning of the equipment.

(4)Meet the aseptic production requirements: optional online CIP (in-situ cleaning) and SP (in-situ sterilization) and online aseptic sampling and other functions, and the upper and lower processes sealed connection, the entire production process closed production, in line with the new version of the GMP production requirements to meet the new version of the production requirements of vitamin E and other aseptic API API production needs.

(5) strong material adaptability

applicable to a variety of material forms: can adapt to the viscosity, poor heat penetration, easy to roll the ball, easy to clump into a block of material drying, for vitamin E APIs with a certain viscosity of the material can also be well dealt with to protect the heat-sensitive materials: the drying process is carried out at low temperatures, the heat-sensitive, crystalline requirements of the material does not produce damage to the ability to maintain the activity and quality of vitamin E so that the active ingredient is not lost. active ingredients are not lost.

(6)Easy operation and maintenance of the equipment

Simple and compact structure: the overall structure of the equipment is relatively simple, covers a small area, no dead angle for internal mixing, the automatic discharge function makes the discharging of materials clean and thorough, and reduces the labor intensity.

Easy to clean and maintain: all parts in contact with the material are made of high quality stainless steel, such as SUS316L, the inner wall is polished to Ra0.4 or less mirror light, smooth surface is not easy to residual material, easy to clean. At the same time, some manufacturers will be equipped with special cleaning devices, such as cleaning gun, etc., to further facilitate the cleaning and maintenance of equipment.

Advanced control system: the use of intelligent control system, can realize the temperature, vacuum and other parameters of the automatic control and adjustment, easy to operate, reduce the cost of manual operation, but also improve the stability and reliability of production.


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